QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Forsythe, W. A. Articles by Simpson, R. C. Search for Related Content PubMed PubMed Citation Articles by Forsythe, W. A. Articles by Simpson, R. C.

Effects of Dietary Protein and Fat Sources on Plasma Cholesterol Parameters, LCAT Activity and Amino Acid Levels and on Tissue Lipid Content of Growing Pigs^1,2,

W. A. Forsythe^3,*, E. R. Miller^4,*, G. M. Hill^*, D. R. Romsos^* and R. C. Simpson

^* Department of Food Science and Human Nutrition and Department of Animal Sciences, Michigan State University, East Lansing, MI 48824 and Standard Brands Inc., Stamford, CT

Young male pigs were used to examine effects of dietary protein and fat sources on plasma cholesterol parameters. Diets providing 16 and 42% of metabolizable energy from protein and fat, respectively, were fed for 12–14 weeks. Protein was derived either from plant sources (50% from soybean meal and 25% each from corn and wheat) or from animal sources (90% from casein and 10% from lactalbumin). The polyunsaturated to saturated fat ratio in the diets averaged 3.0 in the polyunsaturated fat diets and 0.3 in the saturated fat diets. Cholesterol content of the four experimental diets (plant protein-polyunsaturated fat; plant protein-saturated fat; animal protein-polyunsaturated fat; and animal protein-saturated fat) was 0.6 mg/kcal. Consumption of diets containing plant protein rather than animal protein reduced total plasma cholesterol levels by 50 mg/dl; high density lipoprotein (HDL) cholesterol levels were also lowered in pigs fed plant protein. Similarly, plasma cholesterol levels were approximately 40 mg/dl lower in pigs fed the polyunsaturated fat diets than in pigs fed the saturated fat diets. HDL cholesterol levels, however, were unaffected by source of fat fed. These results show that the hypocholesterolemic action of the plant proteins was as great as the hypocholesterolemic action of polyunsaturated fat and that consumption of plant proteins rather than animal proteins resulted in lower plasma cholesterol levels regardless of whether polyunsaturated or saturated fats were fed.

KEY WORDS: • animal protein • plant protein • dietary fat • plasma cholesterol • pig

¹ Published with approval of the Michigan Agricultural Experiment Station as Journal Article No. 9402.

² A preliminary report of this work was presented at FASEB meetings in Dallas, April 1979. Forsythe, W. A., Hill, G., Romsos, D. R., Miller, E. R. & Simpson, R. C. (1979) Effect of dietary protein and fat on growth and blood lipids in pigs. Fed. Proc. 38, 445 (abs).

³ W. A. Forsythe and G. M. Hill were NIH Trainees, Grant # GM 01818. Forsythe's current address is: Department of Nutrition, University of North Carolina, Chapel Hill, NC 27514

⁴ To whom reprint requests should be sent at: Department of Animal Sciences, Michigan State University, East Lansing, MI 48824.

Manuscript received 21 April 1980.