QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Greger, J. L. Articles by Snedeker, S. M. Search for Related Content PubMed PubMed Citation Articles by Greger, J. L. Articles by Snedeker, S. M.

Effect of Dietary Protein and Phosphorus Levels on the Utilization of Zinc, Copper and Manganese by Adult Males^1,2,

Department of Nutritional Sciences, University of Wisconsin, Madison, WI 53706

Zinc, copper and manganese utilization were examined in eight adult males fed a low protein-moderate phosphorus diet (LPrMP), a low protein-high phosphorus diet (LPrHP), a high protein-moderate phosphorus diet (HPrMP) and a high protein-high phosphorus diet (HPrHP) during a 51-day balance study. The low and high protein diets contained 8.1 g and 24.1 g nitrogen daily, respectively. The moderate and high levels of phosphorus were 1,010 and 2,525 mg phosphorus daily. Subjects lost less zinc in the feces when fed the HPrMP diet than when fed the other three diets. The level of dietary protein, the level of dietary phosphorus and the interaction between dietary protein and phosphorus all statistically affected fecal zinc excretion. Urinary zinc excretion was significantly greater when subjects consumed the high protein diets rather than the low protein diets. Apparent retention of zinc was greatest when subjects were fed the HPrMP diet rather than the other three diets. This effect was statistically attributable to the interaction between dietary protein and phosphorus. Serum zinc levels were significantly elevated when subjects consumed the high protein rather than the low protein diets. Serum zinc levels were correlated to urinary zinc excretion (r = 0.788, P < 0.001), apparent retention of zinc (r = 0.385, P < 0.05) and serum copper levels (r = 0.395, P < 0.05). Apparent absorption and retention of copper were significantly greater when subjects were fed the high protein rather than the low protein diets. The dietary treatments did not affect the urinary excretion of copper, serum copper levels or the apparent absorption and retention of manganese by these subjects.

KEY WORDS: • dietary protein • dietary phosphorus • zinc • copper • manganese • human balance study

¹ Research supported by the College of Agricultural and Life Sciences, University of Wisconsin, Madison and by Public Health Service Grant No. 5RO1-AM19290-03.

² Tougas, S., Marcus, R. & Greger, J. L. (1979) Zinc, copper, manganese and selenium balances of adult males fed two levels of protein and phosphorus. Fed. Proc. 38, 1178 (abs.).

Manuscript received 24 February 1980.