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Journal of Nutrition Vol. 11 No. 5 May 1936, pp. 401-409
Copyright © 1936 by American Society for Nutrition
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Lactoflavin, A Necessary Growth-Promoting Dietary Factor

Three Figures

S. Ansbacher, G. C. Supplee and R. C. Bender

The Dry Milk Company Inc., Research Laboratory, Bainbridge, New York

Lactoflavin is a necessary growth-promoting dietary factor. A difference in the rate of growth of white rats results from the differences in the daily intake level of pure crystalline lactoflavin varying from 2.0 to 20.0 {gamma}.

The growth-promoting properties of lactoflavin are readily determined with a suitable basal ration adequately supplemented with pure vitamin B and a third factor or group of factors necessary for the prevention and cure of dermatitis and carried by rice polish.

The potency of lactoflavin may be ‘calculated’ to be 150,000 units per gram. However, as briefly discussed, the ‘unit’ designation for expressing the potency of biological substances, such as vitamins and enzymes, may be meaningless or erroneous.


Manuscript received 6 January 1936.





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