QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Takeda, H. Articles by Kiriyama, S. Search for Related Content PubMed PubMed Citation Articles by Takeda, H. Articles by Kiriyama, S.

Correlation between the Physical Properties of Dietary Fibers and Their Protective Activity against Amaranth Toxicity in Rats¹

Department of Agricultural Chemistry, Faculty of Agriculture, Ehime University, Tarumi-3-5-7, Matsuyama, Japan

The mechanism(s) by which dietary fiber (DF) exerts beneficial effects on the growth of weanling rats fed toxic doses of amaranth (Food & C Red No. 2) was investigated. When crude DF (GDF) prepared from the roots of edible burdock (Arctium lappa L.) were added at graded levels to a purified basal diet supplemented with amaranth (control), growth was improved with increasing GDF level up to and above that of the basal diet-fed group. The correlation equation obtained between the dietary percentage level of GDF (X) and the protective activity (Y) expressed as (difference in body weight gains between rats fed test and control diets) x 100/(difference in body weight gains between rats fed basal and control diets) was Y = 32.6 + 86.9 logX (r = 0.98). The comparative activities at the 5% level of various DF prepared from GDF decreased in the order of holocellulose, neutral-detergent fiber, GDF, crude fiber and acid-detergent fiber. Cellulose from cotton fiber had no activity. The activity was intimately related to their water-holding capacity (WHC) and settling volume in water (SV) (r = 0.90 and 0.96, respectively), but not to the capacity to bind amaranth. The correlation showed a saturation phenomenon quite similar to the equation described above in respect of GDF level. At the 10% level, even cellulose which has a low SV, showed protective activity similar to that of 3% GDF. From these and other results, it was concluded that the protective activity of various DF mainly depends on their physical properties such as SV or WHC.

KEY WORDS: • amaranth toxicity • detoxication by dietary fiber • holocellulose • NDF • ADF • CF • settling volume in water • water-holding capacity • rat

¹ A part of this paper was presented at the 31st annual meeting of the Japanese Society of Food and Nutrition, held in Tokyo, May 20–22, 1977. Takeda, H. & Kiriyama, S. Supported in part by the research grant from the Ministry of Education, Science and Culture (Scientific Research (B), No. 147184).

² To whom reprint request should be addressed.

Manuscript received 26 June 1978.

This article has been cited by other articles:

				T. Morita, H. Tanabe, H. Ito, S. Yuto, T. Matsubara, T. Matsuda, K. Sugiyama, and S. Kiriyama Increased Luminal Mucin Does Not Disturb Glucose or Ovalbumin Absorption in Rats Fed Insoluble Dietary Fiber J. Nutr., October 1, 2006; 136(10): 2486 - 2491. [Abstract] [Full Text] [PDF]