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Journal of Nutrition Vol. 108 No. 8 August 1978, pp. 1244-1249
Copyright © 1978 by American Society for Nutrition
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New Methods for Comparing the Biological Efficiency of Alternate Nutrient Sources1

L. Preston Mercer2, Nestor W. Flodin and Paul H. Morgan

University of South Alabama, College of Medicine, Department of Biochemistry, Mobile, Alabama 36688

The objective of this study is to propose new methods for the determination of biological efficiency (the ability of a nutrient to produce a response) and for comparison of the efficiencies of alternate nutrient sources. The proposed methods are based on a four-parameter kinetic model which describes response as a function of intake. The comparison of the abilities of two proteins (casein and soybean protein concentrate) to promote weight gain in weanling rats is presented as an example; however, the model is also useful for other nutrients (proteins, amino acids, vitamins, minerals, etc.) and other responses (blood enzyme or protein levels, tissue enzyme levels, etc.). Application of the method leads to useful comparisons of nutrient sources as well as information concerning the maximum efficiencies and rates of nutrient utilization from different sources.

KEY WORDS: • computation of biological efficiency mathematical model for nutrient responses

1 These Investigations were supported by intramural monies from the University of South Alabama and Grant No. 5 RO1 AI11527 from the National Institutes of Health.

2 To whom reprint requests should be addressed. Current address: Department of Biochemistry, College of Medicine, Oral Roberts University, Tulsa, Oklahoma 74171.

Manuscript received 24 November 1975.


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A comparison of methods of fitting several models to nutritional response data
J Anim Sci, February 1, 2008; 86(2): 500 - 507.
[Abstract] [Full Text] [PDF]


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