Journal of Nutrition

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Journal of Nutrition Vol. 108 No. 12 December 1978, pp. 1969-1975
Copyright © 1978 by American Society for Nutrition
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Ascorbic Acid and Stress Ulcer in the Rat

Gary B. Glavin1, William P. Paré and George P. Vincent, Jr.

Pavlovian Research Laboratory, Veterans Administration Hospital, Perry Point, Maryland 21902

Rats were orally administered ascorbic acid at a dose of 30 g/liter during either total starvation, partial starvation, the activity-stress ulcer procedure, or the restraint-cold procedure. In four experiments, ascorbic acid failed to exert significant protective action against stomach ulcer formation and, in fact, may have potentiated the ulcerogenic process.

KEY WORDS: • ascorbic acid • starvation • restraint • activity stress • gastric ulcer

1 Present address: Department of Paychology, Brock University, St. Catharines, Ontario, Canada L2S 3A1.

Manuscript received 7 June 1977.




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