QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Johnson, G. H. Articles by Perkins, E. G. Search for Related Content PubMed PubMed Citation Articles by Johnson, G. H. Articles by Perkins, E. G.

Nutritional Implications of the Maillard Reaction: the Availability of Fructose-Phenylalanine to the Chick

University of Illinois, Urbana, Illinois 61801

Fructose-phenylalanine, the Amadori compound resulting when glucose reacts with phenylalanine, was administered to chicks receiving a phenylalanine-deficient crystalline amino acid diet. The chicks did not respond to oral administration of this molecule which indicated it was nutritionally unavailable as a source of phenylalanine. In vitro protein synthesis studies on liver tissue showed that the rate of incorporation of ¹⁴C-phenylalanine into liver solids/mg tissue was significantly lower in chicks fed 0.404%-fructose-phenylalanine than in those not fed this compound. However, when fructose-phenylalanine was added directly to the incubation medium, no reduction of amino acid incorporation occurred. The discrepancy between in vitro and vivo results suggests, therefore, that fructose-phenylalanine is metabolized to another molecule which is causative in reducing liver protein synthesis.

KEY WORDS: • Maillard reaction • phenylalanine • fructose-phenylalanine • growth • protein synthesis

¹ Department of Home Economics, University of Kentucky, Frankfort.

² Department of Animal Science, University of Illinois.

³ Department of Food Science; author to whom all inquiries should be addressed.

⁴ Supported in part by the Illinois Agricultural Experiment Station, Urbana, Illinois.

Manuscript received 21 January 1977.