Journal of Nutrition

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

Journal of Nutrition Vol. 107 No. 5 May 1977, pp. 775-782
Copyright © 1977 by American Society for Nutrition
This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Nishino, K.
Right arrow Articles by Itokawa, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nishino, K.
Right arrow Articles by Itokawa, Y.

Thiamin Metabolism in Vitamin B6 or Vitamin B12 Deficient Rats

Kosuke Nishino and Yoshinori Itokawa

Department of Hygiene, Faculty of Medicine, Kyoto University, Kyoto, Japan

To clarify the effect of pyridoxine (vitamin B6) or vitamin B12 deficiency on thiamin metabolism, the following two experiments were carried out. In experiment 1, rats were separated into two groups. The first group was fed a complete diet and the second group was fed a vitamin B6 and B12 deficient diet for 25 days. The groups were pair fed. In experiment 2, rats were separated into four groups and fed for 25 days. Group 1 was fed a complete diet; group 2, a vitamin B6 deficient diet; group 3, a vitamin B12 deficient diet; group 4, a thiamin deficient diet. Diet intake was restricted to 10 g/day. Fecal thiamin content increased in B6-B12 (vitamin B6 and B12), B6 (vitamin B6), and B12 (vitamin B12) deficient rats as compared to controls. Thiamin levels in blood, sciatic nerve, liver, heart and kidney decreased in B6-B12, B6, and B12 deficient rats.

KEY WORDS: • vitamin B6 deficiency • vitamin B12 deficiency • thiamin deficiency

Manuscript received 11 August 1976.


This article has been cited by other articles:


Home page
 Alcohol AlcoholHome page
M. CECCANTI, R. MANCINELLI, G. F. SASSO, J. P. ALLEN, R. BINETTI, A. MELLINI, F. ATTILIA, L. TOPPO, and M. L. ATTILIA
ERYTHROCYTE THIAMINE (Th) ESTERS: A MAJOR FACTOR OF THE ALCOHOL WITHDRAWAL SYNDROME OR A CANDIDATE MARKER FOR ALCOHOLISM ITSELF?
Alcohol Alcohol., July 1, 2005; 40(4): 283 - 290.
[Abstract] [Full Text] [PDF]


Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]