Journal of Nutrition

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

Journal of Nutrition Vol. 107 No. 4 April 1977, pp. 690-699
Copyright
This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zeman, F. J.
Right arrow Articles by Fratzke, M. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zeman, F. J.
Right arrow Articles by Fratzke, M. L.

Carbohydrate Absorption in the Young of Protein-Deficient Rats1

Frances J. Zeman and Marilyn L. Fratzke

Department of Nutrition, University of California, Davis, California 95616

The absorption of 3-O-methylglucose (TMG) and of lactose has been studied in the young of female rats fed a protein-deficient diet during pregnancy. Postnatally, these young were suckled by stock dietfed dams. Intestines of newborn, 4-day and 12-day old pups were infused in situ with 5% TMG or 3.5% lactose. The mean amount retained per enterocyte was measured as well as the mean amount absorbed from the lumen and transferred from the enterocyte. Absorption of lactose was reduced in the enterocytes of newborn prenatally protein-deprived (PPD) young but not postnatally, while TMG absorption was normal at birth and 12 days but reduced at 4 days. The amount of carbohydrates absorbed in total or per unit intestinal weight seemed to vary with changes in the number of absorptive cells. It is suggested that reduced absorption in PPD pups is primarily related to the smaller number of absorptive cells in these young. There is a greater increase in numbers of cells and in absorption per cell between birth and 12 days in PPD young than in controls, indicating that the effect on the intestine of prenatal protein deprived young is at least partially reversible.

KEY WORDS: • carbohydrate • absorption • pregnant • protein deficient • intestine

1 Supported in part by Public Health Service Research Grant No. HD-06465 from the National Institute of Child Health and Human Development.

Manuscript received 4 May 1976.




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]