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Magnesium, Calcium and Zinc Levels of Maternal and Fetal Tissues in Magnesium Deficient Rats¹

Department of Nutrition, University of California, Davis, California 95616

The interaction of magnesium with two other mineral elements, calcium and zinc, was studied in maternal tissues and fetuses of pregnant rats fed a magnesium deficient diet throughout gestation. Reduction in maternal femur magnesium and a trend for increased kidney calcium reflected the dietary magnesium deficiency. In fetuses, however, total magnesium content was reduced and, in addition, fetal zinc content was also lower than normal in the group most severely deficient in magnesium. The possible interpretation of this magnesium-zinc interaction is discussed.

KEY WORDS: • magnesium • calcium • zinc • fetal • pregnancy

¹ Supported in part by research grant HD-01743 from the National Institute of Child Health and Human Development.

Manuscript received 13 February 1976.