Journal of Nutrition

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Canolty, N. L.
Right arrow Articles by Nasset, E. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Canolty, N. L.
Right arrow Articles by Nasset, E. S.

Intestinal Absorption of Free and Protein-bound Dietary Methionine in the Rat1

Nancy L. Canolty2 and E. S. Nasset

Department of Nutritional Sciences, University of California, Berkeley, California 94720, and Children's Hospital Medical Center, Bruce Lyon Memorial Research Laboratory, Oakland, California 94609

Intestinal absorption of radioactive free and protein-bound dietary methionine (Met) and changes in plasma amino acids were observed after feeding Met-supplemented test meals. Plasma and gastrointestinal contents were collected from 15 minutes to 16 hours after feeding. Plasma amino acids were determined after ad libitum ingestion of diets containing free Met. Protein-bound Met in fresh egg white and free Met left the stomach at the same rate, but protein-bound Met in dried egg white and free Met were emptied from the stomach at different rates. Free Met was absorbed from the intestine more rapidly than protein-bound Met. Concentrations and molar ratios of various free amino acids in plasma changed briefly in response to Met-supplemented single test meals. Long-term changes were observed when Met-supplemented diets were fed ad libitum. Prolonged ingestion of supplemented diets may cause sustained alterations in the plasma amino acid pattern.

KEY WORDS: • intestinal absorption • plasma amino acids • methionine • supplemented diets

1 Based on a dissertation presented by Nancy L. Canolty to the Department of Nutritional Sciences, University of California. Berkeley, as partial fulfillment of the requirements for the Ph.D. degree. Supported in part by USPHS Training Grant, 5T1GN 11 SS08. Research Grant AM-15446, and a grant from the National Live Stock and Meat Board.

2 Present address: Department of Nutrition, University of California, Davis, Calif. 95616.

Manuscript received 16 October 1974.




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Copyright © 1975 by American Society for Nutrition