QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Clamon, G. H. Articles by Henderson, W. R. Search for Related Content PubMed PubMed Citation Articles by Clamon, G. H. Articles by Henderson, W. R.

Effect of -Retinyl Acetate on Growth of Hamsters Fed Vitamin A-deficient Diets

Lung Cancer Branch, National Cancer Institute, Bethesda, Maryland 20014

The capacity of the isomer of retinyl acetate to support growth in hamsters fed a vitamin A-deficient diet was assessed over a 40-fold dose range. Although decreased relative potency of the isomer, as compared with the ß isomer, was found, sustained weight gain and survival for 6 months were achieved with a weekly intraperitoneal dose of 300 µg of the isomer. An intraperitoneal dosage of -retinyl acetate resulted in greater activity than an oral dosage.

KEY WORDS: • vitamin A • -retinyl acetate

¹ To whom requests for reprints should be sent.

Manuscript received 22 July 1974.