QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Zile, M. Articles by DeLuca, H. F. Search for Related Content PubMed PubMed Citation Articles by Zile, M. Articles by DeLuca, H. F.

Vitamin a and Bone Metabolism in the Rat¹

Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706

The mobilization of calcium from bone in the rat was found to be unaffected by vitamin A deficiency. Furthermore, the mechanisms that regulate high serum calcium levels function normally in vitamin A deficiency suggesting no impairment of calcitonin secretion. However, vitamin A deficiency lowers alkaline phosphatase activity of plasma and bone and increases hydroxyproline concentration of the plasma which implies some role of vitamin A in the metabolism of bone.

KEY WORDS: • retinol • calcium • alkaline phosphatase • hydroxyproline • bone

¹ Supported by a grant from the National Institutes of Health, no. AM-14881.

² To whom requests for reprints should be addressed.

Manuscript received 24 July 1972.

This article has been cited by other articles:

				D. T. Shaw, D. W. Rozeboom, G. M. Hill, M. W. Orth, D. S. Rosenstein, and J. E. Link Impact of supplement withdrawal and wheat middling inclusion on bone metabolism, bone strength, and the incidence of bone fractures occurring at slaughter in pigs J Anim Sci, May 1, 2006; 84(5): 1138 - 1146. [Abstract] [Full Text] [PDF]