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Depression of Plasma Cholesterol in Calves by Supplementing a High Cholesterol Liquid Diet with Dry Feed1,2,

N. L. Jacobson, M. Richard and P. J. Berger

Department of Animal Science, Iowa State University, Ames, Iowa 50010

Young calves were fed whole milk with cholesterol added at 25, 100, 175 and 250 mg per kilogram calf weight daily for 8 weeks. Half the calves at each level also were fed a dry starter diet. All received a vitamin-mineral supplement in the milk. Plasma cholesterol of milk-fed, 25-mg-level calves plateaued at approximately 150 mg/100 ml; that of the other milk-fed calves plateaued at about 250 mg, with no significant differences among the three higher cholesterol-intake groups. Maximum absorption as measured by plasma cholesterol was reached at the 100-mg level of intake, in which dietary cholesterol:fat was approximately 1:31. Plasma cholesterol of the 25-mg-level calves fed milk and starter was similar to that of the same group fed no starter. Higher dietary cholesterol for calves fed milk and starter effected no additional response; maximum absorption was reached at a dietary cholesterol:fat ratio of about 1:95. Thus, feeding starter markedly suppressed plasma cholesterol despite similar intakes of cholesterol and fat in calves fed the two types of diet. After removal of cholesterol from the diet and restriction of the diet to starter only, cholesterol levels declined rapidly to about 100 mg/100 ml plasma.


KEY WORDS: • cattle • cholesterol absorption

1 Journal Paper no. J-7365 of the Iowa Agriculture and Home Economics Experiment Station, Ames, Iowa, Project no. 1908.

2 Supported in part by funds provided by Grant no. HE-04969, Department of Health, Education and Welfare.

Manuscript received 10 October 1972.





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