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Journal of Nutrition Vol. 101 No. 12 December 1971, pp. 1663-1671
Copyright © 1971 by American Society for Nutrition
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Effect of Maternal Protein Deprivation on Neonatal Intestinal Absorption in Rats

Kuei-Rong W. Loh, Ruth E. Shrader and Frances J. Zeman

Department of Nutrition, University of California, Davis, California 95616

The effects of maternal protein deficiency on intestinal absorption in neonatal rats were studied. Female rats were fed diets adequate or deficient in protein throughout gestation. Newborn young of the females fed the protein-deficient diet, taken by cesarean section on day 21 of gestation, showed histological evidence of decreased uptake of protein and fat by jejunal enterocytes. Cells in which the absorptive defect was most evident lacked well defined brush borders and showed decreased content of cytoplasmic organelles. In these young, abnormalities of morphological development can be correlated with reduced functional activity.

KEY WORDS: • protein • absorption • neonatal • intestinal morphology

Manuscript received 15 June 1971.




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