QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Stephan, J. K. Articles by Chow, B. F. Search for Related Content PubMed PubMed Citation Articles by Stephan, J. K. Articles by Chow, B. F.

Relationship of Growth Hormone to the Growth Retardation Associated with Maternal Dietary Restriction¹

The Johns Hopkins University, School of Hygiene and Public Health, Department of Biochemistry, Baltimore, Maryland 21205 and Department of Medicine, State University of New York at Buffalo, Buffalo, New York 14215

The progeny of rats whose dietary intake was restricted during gestation and lactation were compared with the progeny of ad libitum-fed mothers with respect to pituitary weight and growth hormone activity by bioassay and radioimmunoassay, both groups having been fed ad libitum after weaning. The offspring of the underfed dams had smaller pituitaries containing lower concentrations of growth hormone; all differences were statistically significant. These animals responded with increased weight gain to administration of growth hormone.

Manuscript received 17 February 1971.

This article has been cited by other articles:

				C. D Byrne Programming other hormones that affect insulin: Type 2 diabetes Br. Med. Bull., November 1, 2001; 60(1): 153 - 171. [Abstract] [Full Text] [PDF]