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Divisi1on of Nutrition, Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37203
Vitamin E deficiency in rabbits results in a large increase in liver xanthine dehydrogenase activity, suggesting that vitamin E regulates the synthesis of this enzyme. It is postulated that increased liver xanthine dehydrogenase activity may be responsible for the anemia observed in vitamin E-deficient animals.
2 Associate Director, Biomedicai Sciences, The Rockefeller Foundation, New York. Visiting Professor, Department of Biochemistry, Vanderbilt University School of Medicine, February-October, 1970.
Manuscript received 25 November 1970.