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Nutritional Contribution of Volatile Fatty Acids from the Cecum of Rats¹

Foods and Nutrition Department, Michigan State University, East Lansing, Michigan 48823

The contribution of cecal acetic, propionic and butyric acids to rats' energy metabolism amounted to 4.7% of the caloric intake. This was determined by measuring rates of disappearance of these volatile fatty acids (VFA) from the cecum of rats killed at various intervals after the last meal. Further support indicating that VFA are energy sources for rats came from the appearance of ¹⁴CO₂ in the breath when radioactive VFA were placed in their cecum.

Manuscript received 24 November 1969.

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