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The Differential Antirachitic Activity of Vitamin D Milks¹

Department of Agricultural Chemistry, University of Wisconsin, Madison

Briefly, the results of our experiments show that for the chick and per unit of vitamin D:

1. Irradiated milk, cod liver oil, and irradiated cholesterol are of approximately the same order of effectiveness.

2. Yeast milk is approximately one-tenth as effective as irradiated milk. This difference was confined to the respective butter fat fractions and was not influenced by the skimmed milk fraction.

3. The constituents of milk as a vehicle for vitamin D do not influence its effectiveness.

4. Our experiments give no support to the possibility that the baby chick could be used to greater effectiveness than the rat for ascertaining the degree of antirachitic effectiveness of different vitamins D for the human.

A preliminary report of the data in this paper was presented before the American Institute of Nutrition, April 10, 1935. Similar data were presented by Bethke, Krauss, Record and Wilder, Proc. Am. Inst. Nutrition, J. Nutrition, vol. 9, suppl. p. 7, 1935.

Manuscript received 9 September 1935.