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Journal of Nutrition Vol. 10 No. 6 December 1935, pp. 599-611
Copyright © 1935 by American Society for Nutrition
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Selenium in Proteins from Toxic Foodstuffs1

IV. The Effect of Feeding Toxic Proteins, Toxic Protein Hydrolysates, and Toxic Protein Hydrolysates from which the Selenium Has Been Removed

Two Figures

Kurt W. Franke and E. Page Painter

Department of Experiment Station Chemistry, South Dakota State College, Brookings

The effect of chemical treatment of the proteins from toxic wheat has been studied by animal feeding. Growth curves of animals fed diets containing whole grain, protein, protein hydrolysate and protein hydrolysate after mercuric chloride precipitation are shown.

From the results obtained by the separation trials and feeding series, the following conclusions are made:

1. The sulfuric acid hydrolysates of toxic proteins are toxic.
2. Mercuric chloride precipitation of toxic protein hydrolysates (under the proper conditions) precipitates the selenium compound (or compounds) so nearly completely that the filtrate is innocuous when fed to albino rats.
3. Mercuric chloride precipitation removes something from sulfuric acid hydrolysates which directly or indirectly inhibits growth.

1 Published with the permission of the director of South Dakota Agricultural Experiment Station as communication no. 17 from the department of experiment station chemistry. These investigations are being carried out under the Purnell Fund and with the cooperation of the Bureau of Chemistry and Soils, Bureau of Plant Industry, Bureau of Animal Industry, and Bureau of Home Economics of the United States Department of Agriculture.

Manuscript received 23 August 1935.




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