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On the Carbon: Nitrogen (C/N) Ratio in the Urine of Rats Deprived of One or Both Factors of the Vitamin B Complex

(From the Anatomical Laboratory, University of California, Berkeley)

Rats kept on a diet deficient in the heat-stable component of the vitamin B complex show an increased carbon: nitrogen ratio in the urine as compared with individual controls receiving equivalent amounts of a complete diet. This difference is less marked for animals deprived of the whole vitamin B complex and is negligible in the case of rats receiving autoclaved yeast. We may, therefore, entertain the hypothesis that the heat-stable factor is in some way linked with the metabolic processes of the body.