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Figure 1


FIGURE 1  The first two steps in the BCAA catabolic pathway. KIV, {alpha}-ketoisovalerate; KMV, {alpha}-keto-ß-methylvalerate; KIC, {alpha}-ketoisocaproate; CoA-SH, coenzyme A, reduced form; IB-CoA, isovaleryl-CoA; MB-CoA, {alpha}-methylbutyryl-CoA; IV-CoA, isovaleryl-CoA; R-CoA, acyl-CoA; Pase, phosphatase. Adapted from Shimomura et al. (9).